Seizure is the most common presenting symptom and is seen in approximately 75% of cases. Fetal anatomy may not be visualized due to fetal position, maternal body habitus, late or early gestational age, or low amniotic fluid levels Fetal biometry will assess growth if gestational dating is known, but if dating is unknown biometry will be used to assign gestational age. Induction is usually avoided as it is associated with a higher risk of rupture: Caesarean is preferable unless the cervix is ripe or the fetal head is engaged. C Structural causes of abnormal uterine bleeding include fibroids, endometrial polyps, adenomyosis, and malignant tumors of the uterus including sarcoma or endometrial cancer. Classically, the bone anterior to the oval window (fissula antefenestram) is involved. These children are at risk for behavior and school problems, substance abuse, and violent relationships as adults. Postpartum hemorrhage is defined as a blood loss in excess of 500 mL during the first 24 hours after vaginal delivery. Ninety-five percent of adult hemoglobin is hemoglobin A (made by two -chains and two -chains). Differential Diagnosis Epidermoid or dermoid Lymphangioma Abscess Teaching Points A ranula is a mucous retention cyst that involves the sublingual salivary gland. She is concerned with the risks that rubella infection can have on the developing fetus and desires vaccination. The methods used will vary according to pregnancy risk and events during the pregnancy. Perinatal death may indicate an underlying problem that may or may not have been detected previously, such as: a. Hence, not all vitamin B12 deficiency is on the basis of pernicious anemia, and it may be correctable with oral vitamin B12 supplementation. C atastrophic neurologic injury is often quite obvious even within hours after presentation. Breast development is normal, as the androgens produced by the testes are aromatized to estrogens leading to breast development. Medical means of inducing abortion include extrauterine and intrauterine administration of abortifacients, such as prostaglandins, hypertonic saline, and oxytocin. Hysterosalpingogram, sonohysterogram, or hysteroscopy to evaluate the uterine cavity. However, to date, clinical trials have failed to demonstrate cardiovascular event reduction with ezetemibe. Adolescent patients have short stature, lack of sexual maturation, a low posterior hairline, prominent ears, a broad chest, widely spaced nipples, and epicanthal folds. Anthropoid-diameter is long from front to back and relatively narrow from side to side. In some developing countries, where Pap smears are not routinely performed, cervical cancer remains the most common cause of cancer death in women. It is also found in the Japanese lacquer tree, mango rinds, cashew shell oil, and the seed coat of the ginkgo tree. Choroid plexus tumors occur more commonly within the lateral ventricles in children, and within the fourth ventricle in adults. They are typically iso- to hypointense on T2-weighted images and enhance intensely. Treatment beyond this period has not found to be effective and may in fact be harmful. The patient with the insulinoma was managed with a spleen-preserving distal pancreatectomy. Sexual assault is a form of sexual activity that occurs without the consent of the victim and includes the use of force, implied force, or deception on the part of the assailant. The maternal mortality rate for blacks has also declined, but it remains higher than for white women (26. Increased attention was drawn to this entity by the Mayo Clinic report of six patients with this disorder following Roux-en-Y gastric bypass surgery. The incidence of placenta accreta increases to more than 50% after four previous cesarean sections. For women with a bicornuate uterus or uterine didelphys, careful obstetric management is the preferred approach.
The most common history is indolent personality change and mental status disturbance. Chorionicity is most accurately ascertained in the first trimester: in dichorionic twins, the dividing membrane is thicker as it meets the placentas (Lambda sign). Malignant degeneration of spinal nerve sheath tumors, although rare, is characterized by rapid growth. Information on prevention in perimenopausal women or those with premature ovarian failure is scant. This type of digital block provides complete anesthesia distal to and including the distal interphalangeal joint, the site that most often demands a nerve block. C Timing Cerclage is usually performed between the 12 and 16 weeks of gestation but can be performed as late as the 24 weeks of gestation. In these patients, there is significant apical ballooning from a major sympathetic outburst associated with acute brain injury, in turn resulting in severe pulmonary edema. He has very frequent spontaneous multifocal myoclonus involving the face and all limbs. Enterocele is protrusion of small bowel behind the upper vaginal wall in to the vaginal canal. For both conditions, topical agents are seldom helpful and oral drugs such as amitriptyline or gabapentin are sometimes used. A classical uterine incision (vertical uterine incision through the muscular portion of the uterus) is a contraindication to a trial of labor and vaginal delivery with a subsequent pregnancy. Radical vulvectomy may be partial or total, depending on the size and location of the lesion. Fetal skin sampling can be performed to obtain fetal cells, usually to diagnose severe skin conditions such as epidermolysis bullosa. Earlier names for forms of this disease include Shy-Drager syndrome, striatonigral degeneration, and olivopontocerebellar atrophy. Later pregnancy screening Ultrasound for structural abnormalities An ultrasound examination should be offered at 20 weeks. Retinoblastomas that are confined to the globe have a good overall prognosis, whereas those that extend outside of the globe have nearly 100% 5-year mortality. Endoscopy and endoscopic surgery Diagnostic hysteroscopy the uterine cavity is inspected with a rigid or flexible hysteroscope passed through the cervical canal. Some women find them inconvenient, and they are best suited to a woman with good motivation. Women with a history of prior cesarean section are at greater risk for placental abnormalities such as placenta previa and placenta accreta. Superficial thrombophlebitis of legs, but not pelvic vessels, may result from stasis of blood in this patient. For description of injuries, dated photographs are ideal, but body maps or written descriptions are also acceptable. In addition, the increase in rates of exchanging sex for crack cocaine has increased the number of cocainecomplicated pregnancies. The thick protective stratum corneum of the palms and the soles generally protects these areas. Postoperative pneumonia, deep vein thrombosis, and pulmonary embolus are of particular concern in morbidly obese subjects, and appropriate preventive measures need to be in place. Ectopic ureter is a condition in which the ureter terminates in a site other than the bladder as it normally should. Given that she has been on oral contraceptive pills for endometrial protection, an endometrial biopsy is not warranted at this time. The theoretical advantages of this operation over hysterectomy, as well as preservation of fertility, are a stronger repair, with less risk of recurrent prolapse. We favor the more conservative approach of proceeding with a percutaneous tracheostomy at least 10 days after the start of mechanical ventilation and when need for more than 3 weeks of mechanical ventilation is anticipated. Fifty per cent of affected infants have a chromosomal problem and amniocentesis is offered. Hysteroscopic surgery An operating hysteroscope is used in which small instruments are passed down a parallel channel.
Clinical presentation (1) this anomaly has a marked association with early pregnancy loss, or recurrent spontaneous abortion, mid-trimester loss, and preterm birth. In a population of 550 French women who acquired toxoplasmosis during pregnancy, 61% of the neonates had evidence of congenital infection; of these neonates, 6% died, 5% had severe clinical illness, 9% had mild disease, and 41% had subclinical disease. Although the length of the menstrual cycle may vary from woman to woman, it usually remains the same in a particular individual. On T2*-weighted (gradient-echo) sequences the hematoma will demonstrate susceptibility-related signal loss. Worsening can also occur because of hemorrhage in the surgical bed, remote hemorrhage, cerebral edema, or ischemic stroke from sacrifice of a large vein or artery. A position statement of the American Diabetes Association, a scientific statement of the American Heart Association, and an expert consensus document of the American College of Cardiology Foundation. Physician should respect cultural and religious beliefs, but these may be an impediment to rational medical care. Patients have varying degrees of fusion of the hemispheres, basal ganglia, hypothalami, and thalami. The following percentages reflect the prevalence of these factors in infertility evaluations. It is important to ascertain the status of the stapes footplate (oval window) and round window prior to surgical intervention. The enzyme activity is partly stimulated by elevated circulating testosterone levels. It is also common for acute symptoms to have no obvious cause and spontaneously resolve over the course of a few weeks. According to the Council on Child and Adolescent Health, such preventive counseling is particularly important at the precollege visit. When necessary, the primary treatment is surgical resection with or without radiation therapy. A guarded attitude toward these massive cerebral infarcts is understandable, but surgical treatment may be beneficial in some cases. Ipsilateral inguinal and femoral lymphadenectomy may be considered when the lesion is well lateralized. Because of an approximately 25% risk of progression to endometrial carcinoma, hysterectomy is the treatment of choice for this condition. Estrogen levels are normal or elevated so there is not an acceleration of bone loss. However, this decreased requirement is seen in the first trimester, well before significant mechanical changes have occurred. The risks are dose dependent, higher with multiple drug usage and higher with certain drugs. Other gastrointestinal causes of chronic pelvic pain include constipation, inflammatory bowel disease, and carcinoma of the colon. Progestogen given continuously with daily estrogen does not induce cyclic bleeding but is associated with unpredictable irregular bleeding in up to 40% of women in the first 6 months of therapy. Significant pelvic adhesions with or without associated inflammatory cells or hemosiderin-laden macrophages often result. Health promotion and advice Drugs Medications are generally avoided in the first trimester, but teratogenicity is rare. Multiple surgical abortions are Disorders of Early Pregnancy 123 associated with an increased risk of subsequent preterm delivery (p. If symptoms arise from a lingual thyroid, either surgical excision or iodine-131 ablation can be performed. Insulin will be required in the rest, particularly where fasting glucoses are high. Management: Most infected neonates are still not seriously affected: close surveillance for ultrasound abnormalities, and fetal blood sampling at 32 weeks for fetal platelet levels, may help determine those at most risk for severe sequelae. The most significant causes are fibroids, adenomyosis, endometriosis, pelvic inflammatory disease and ovarian tumours, which should be treated appropriately.
A rectocoele often causes no symptoms, but occasionally causes difficulty in defaecating. Aggressive surgical management is not indicated if there is pain only and no major neurologic deficit. Ovulation is suppressed by a complex mechanism involving androgens and insulin in the ovary. In these cases, each duct essentially develops in to a separate hemiuterus, each with its own fallopian tube and cervix. The diagnostic test for insulinoma is a 72-hour fast; an inappropriate insulin:glucose ratio is generally found early on. Torsion of fibroids, particularly pedunculated myomas, may cause acute or gradual pain. Anencephaly causes lack of production of this hormone Endocrinology of Pregnancy 9 Answers and Explanations 1. However, given the subthreshold dose and the clinical need to rule out a serious medical complication, the patient should be encouraged to consent to the study. Major causes of maternal death in nonabortive pregnancies (excluding ectopic pregnancies) are, in descending order, hypertensive disorders of pregnancy, obstetric hemorrhage, and thromboembolism. A second study, not yet published, reported a significantly higher risk with the patch compared with the oral contraceptive. Finding an antidote will be important because these new expensive drugs may replace warfarin in the long run. A hand in the uterus, under general or spinal anaesthesia, gently separates the placenta from the uterus, with the second hand on the abdomen preventing the uterus from being pushed up. Diagnosis is usually made by history and simple examination of these familiar-appearing growths. Level of arousal: disorientation, euphoria, sedation, agitation, hallucinations, slurred speech, unsteady gait, yawning, papillary dilation, or constriction 2. Influenza A (1) Characterized by sparse sputum production and interstitial infiltrates (2) Usually self-limited but can be complicated by secondary bacterial pneumonia d. The pain may become severe and diffuse and may be associated with shoulder pain (caused by diaphragmatic irritation from intra-abdominal blood) if significant intra-abdominal hemorrhage exists. Removing the corpus luteum at this early stage of pregnancy will have an adverse effect on the pregnancy because until 8 weeks of gestation the pregnancy is dependent on the production of progesterone from the corpus luteum for support. Because of delayed apoptotic cell death, a post-anoxic leukoencephalopathy may become visible days to weeks after the initial insult. Hemoglobin and hematocrit are obtained in cases of excessive vaginal bleeding to assess the degree of anemia and adequacy of replacement. For example, heparin is not teratogenic because, unlike warfarin, it cannot cross the placenta because of its large molecular weight. The femoral and inguinal lymph nodes receive the lymphatic drainage from the vulva. Continued nursing is usually possible, but mechanical pumping may be necessary on the affected side until the acute inflammation has subsided. The edema in angioedema is found in the deep dermis or subcutaneous/ submucosal tissues. Subsequent molar pregnancies may be complete or partial, regardless of the type of initial molar pregnancy. However, cystometry is generally not indicated until either there has been Anticholinergics (antimuscarinics) suppress detrusor overactivity and are the most widely used treatment. B Lie of the fetus is the relation of the long axis of the fetus to the long axis of the mother and is either longitudinal or transverse. Although these women cannot carry a pregnancy due to uterine abnormalities, they can have oocytes retrieved for in vitro fertilization and have embryos transferred to a gestational carrier. Anorexia nervosa, a condition characterized by extreme weight loss with no known organic cause, can affect adolescent development and result in amenorrhea.
Neuroimaging advances in holoprosencephaly: Refining the spectrum of the midline malformation. Ask about past methods of contraception and why the patient discontinued them can provide useful information for contraceptive counseling. It is usually secondary to a small bruise at the site and lasts for approximately 3 days. Rectocoele is prolapse of the lower posterior wall of the vagina, involving the anterior wall of the rectum. An episiotomy has been advocated in order to prevent major perineal lacerations, particularly at the time of operative vaginal delivery. Hysterectomy should not be performed on the assumption that the bleeding is caused solely by the leiomyomas. Differential Diagnosis Labyrinthitis ossificans Cochlear hypoplasia/aplasia Teaching Points Labyrinthitis ossificans is the end stage of labyrinthitis. Therefore, an early menarche, late menopause and nulliparity are risk factors, whilst pregnancy, lactation and use of the pill are protective. In other patients there may be no direct correlation, and a carotid or basilar artery occludes from progressive atherosclerotic disease, such as in our patient example. Some of these infections cause circular lesions that result from the inflammatory reaction, forcing the dermatophytes outward to an inflammation-free area. Patients are at risk for intracerebral or subdural hemorrhage when the flow through the fistula is directly in to a cortical vein or if it refluxes from a dural sinus in to a cortical vein. The maternal mortality ratio is the number of maternal deaths per 100,000 live births. The mass is homogeneously T1-hypointense and T2-hyperintense with no significant enhancement on postgadolinium images. Weight loss is seen in approximately 75% of patients; this helps motivate ongoing patient adherence. After menopause, there is a shift in the maturation index, with a preponderance of immature cell types (basal and parabasal) over mature cell types (intermediate and superficial). Useful modalities for the screening of vasospasm and diagnosis of delayed cerebral ischemia are summarized in Table 9. They are an incidental finding (usually at autopsy) and generally produce no symptoms or hemorrhage. This method neither allows for visualization of the external surface of the tubes nor provides external assessment of pelvic adhesions or anatomic relationships within the pelvis. Or there may be sufficient haemolysis to cause neonatal anaemia (haemolytic disease of the newborn). Fetal anatomy is best evaluated during the second trimester, and most routine ultrasounds are performed at that time. Newer techniques include a microwave probe or thermal balloons passed in to the uterine cavity which heat and destroy the endometrium, and have a lower risk of uterine perforation. Complications include wound breakdown, infection, leg lymphoedema, lymphocyst formation and sexual and body image problems. Oral clindamycin or metronidazole may be added to doxycycline if an abscess is suspected. Before 20 weeks a uterus that is larger than expected could be due to incorrect dates, a full bladder, multiple pregnancy, uterine fibroids or a pelvic mass. In adults, the imaging appearance of atypical inflammatory adenitis is difficult to differentiate from necrotic lymphadenopathy related to metastatic squamous cell cancer. As part of the screening for dysautonomia, patients should also be carefully examined for development of adynamic ileus. Menometrorrhagia is irregular menstrual bleeding or bleeding that occurs between regular cycles, that is, excessive in amount or duration. The polypropylene tape is passed via the transobturator foramen, through the transobturator and puborectalis muscles. The mass is hyperintense on T2-weighted images, demonstrates heterogeneous enhancement, and has no restricted diffusion.
Brain radiation can also damage the hypothalamus and pituitary; the pituitary is more radiosensitive. Finally, diabetes insipidus may be one of the first signs that a patient is meeting criteria for brain death. Breast conservation (lumpectomy) requires surgical excision of the primary tumor with clear microscopic margins, generally followed by radiation therapy to eradicate potential residual microscopic disease in the breast. Typical imaging findings include: Focal cord kinking with anterior or anterolateral displacement Focal spinal cord thinning and enlargement of the dorsal subarachnoid space It may be difficult to differentiate spinal cord herniation from a dorsal intradural arachnoid cyst. The patient likely suffered anoxic-ischemic injury in addition to traumatic diffuse axonal and contusional brain injury, and reversal of this condition is not likely. Nonreassuring fetal status based on heart rate pattern, auscultation, lack of response to scalp stimulation, or scalp pH 2. This has meant a loss of operator skills, and most preterm breeches now undergo Caesarean section. The dosing schedule is 200 mg twice a day for 5 days, then 100 to 200 mg daily for 6 months. Plasma inorganic iodine concentration decreases because of increased renal excretion and increased glomerular filtration. Radiation therapy, although useful for the reduction of mass effect in the longer term, is characteristically associated with worsening inflammatory edema in the early phase. Such assaults may lead to placental abruption; fetal fractures; rupture of the uterus, spleen, or liver; and preterm labor. Patients present with fever, headache, rapidly progressive cognitive decline, and focal neurologic deficits. These block the muscarinic receptors that mediate detrusor smooth-muscle contraction, relaxing the detrusor muscle. Intrauterine infection, with premature rupture of membranes and preterm delivery 2. Corticosteroids in patients with acute bacterial meningitis, however, remains common practice irrespective of the organism. Fetal glucose levels are directly proportional to maternal glucose concentrations. This can lead to chronic pelvic pain if there is functional endometrium in an obstructed uterine remnant, or if an obstruction in the outflow tract has lead to significant endometriosis and adhesive disease due to retrograde menstrual flow in the setting of delayed diagnosis. Unfortunately this is a difficult task as the currently used techniques have only an average positive predictive value. In general, infants born to epileptic mothers have a 6% to 7% incidence of major and minor congenital abnormalities. The risk of uterine rupture after one previous low transverse type of cesarean section is less than 1%. Fixed and dilated pupils throughout the resuscitation procedure usually indicate a poor chance of success. Phenytoin and Fluconazole Mode of action: Fluconazole inhibits phenytoin metabolism and may increase phenytoin level up to 4 times. Metabolic Syndrome the prevalence of the metabolic syndrome is on the rise-not unexpectedly, given the associations with obesity and glucose intolerance. She was discharged home after 15 days of hospital stay and returned to work 5 weeks later. Other patients fail to get any better, and some others develop hemorrhagic conversion or a large intracerebral hematoma. Postexposure prophylaxis should be considered when contact with a bat or a bite from a bat is possible but uncertain, such as when a bat is found near a sleeping person or a previously unattended child and the animal is unavailable for testing. Homebirth: Progress and fetal condition are monitored in the normal way and nonepidural analgesia may be administered. Breech presentations are classified according to the position of the legs and buttocks, which present first. Upon questioning, the intensive care nurse tells you that the patient is not on any sedative drugs and fentanyl infusion was discontinued 4 hours ago.
Cycle length remains longer than 21 days but is typically shorter than cycles experienced during the reproductive years. When the baby takes his first breath, resistance in the pulmonary vessel circuit is substantially reduced, and thus blood can flow through the pulmonary artery to the lungs (instead of to the aorta through the ductus arteriosus) to become oxygenated. Normal parturients are less responsive to vasopressors and chronotropic agents, such as ephedrine and phenylephrine or ephedrine. Although this patient has normal blood pressures and only mild proteinuria, her blood pressure measurements have been rising steadily over the last few visits. Rate per 100 000 maternities Examination General health and nutritional status are assessed. Sublingual space infections lie above the attachment of the mylohyoid muscle to the mandible, whereas submandibular infections are below. This treatment is appropriate to control pain associated with menstruation and ovulation with endometriosis. At term, induction of labor is indicated if there is no labor within 6 to 24 hours of rupture or if there is any evidence of infection (chorioamnionitis). Moreover, pulmonary infections and atelectases can make weaning even more challenging. The septum can also have a microperforation allowing egress of menstrual blood and presents as a shortened vagina with no visible cervix. Thecomas are very rare, usually benign, and can secrete both oestrogens or androgens. Alogarithms are complex: a simplified version, only for postnatal thromboprophylaxis, is presented. Occipito-transverse position: Usually this is a result of insufficient descent of the head to make it rotate. Hysterectomy is a treatment option for patients who do not desire future fertility. Follow-up should follow the American Society for Colposcopy and Cervical Pathology guidelines and include: (1) Cytologic evaluation every 3 to 6 months for the first year posttreatment (2) Repeat colposcopic evaluation for persistent or recurrent abnormalities (3) Hysterectomy for patients who have persistent severe lesions despite repeated conservative local destructive techniques C Microinvasive carcinoma of the cervix Much controversy surrounds the exact definition of "early" invasive cancer of the cervix. Has been shown to prevent and treat osteopenia and osteoporosis and decrease incidence of bone fractures. Clinical signs and symptoms include learning difficulties, behavioral problems, abnormal skin pigmentation, adrenal insufficiency, and disorders of gait, vision, and hearing commonly in preteen boys. Early performance of tracheostomy (sometimes as early as within the first week of mechanical ventilation) has been proposed in patients expected to require prolonged mechanical ventilation; however, the value of this practice has not been proven. This type of pregnancy loss occurs when there has been partial but incomplete expulsion of the products of conception from the uterine cavity. Acute hypoxia in labour can be due to placental abruption, hypertonic uterine states and the use of oxytocin, prolapse of the umbilical cord and maternal hypotension. Differential Diagnosis Schwannoma Glomus vagale Lymphadenopathy Aneurysm Teaching Points Carotid body tumors are paragangliomas that arise at the carotid bifurcation. It provides an environment in which capacitation of spermatozoa, fertilization, and early development of the embryo take place. It is endemic in heterosexual populations in some parts of Africa, India, Southeast Asia, and the Caribbean. Differential Diagnosis Ranula, infected Lymphangioma Submandibular gland neoplasm Teaching Points Inflammatory disease involving the submandibular space and/or sublingual space is most commonly the result of spread of infection from dental disease. It is most useful where oral bisphosphonates are contraindicated or with malabsorption. It may have a similar appearance to pineoblastoma and should be included in the differential of a solid pineal region mass. It is difficult to know how much each fetus/placenta directly contributes to serum markers in maternal blood. Lichen sclerosus presents as extremely pale, thin skin, often with subepithelial hemorrhages.
The amniotic fluid contains fetal cells, which can be cultured and evaluated for chromosomal abnormalities and molecular testing. The ectopic can also be naturally aborted either within the tube or extruded through the fimbrial end. In the lateral wall of the round mid-pelvis, bony prominences called ischial spines are palpable vaginally. Pleomorphic xanthoastrocytoma: favorable outcome after complete surgical resection. Malignancy: A bloody and offensive discharge is suggestive of cervical carcinoma, but any genital tract malignancy can be responsible. The incubation period of rabies varies from weeks to months, roughly in proportion to the length of the axons on which the virus must propagate to the brain, which is why prophylaxis is especially urgent in facial bites. Common side effects include fever, nausea and vomiting, diarrhea, and uterine hyperstimulation. A 31-year-old woman with diabetes mellitus presents for preconception counseling to discuss the potential impact of her disease on pregnancy. Microbiology: applicator swabs may also be blindly inserted to determine the vaginal flora. Terminal is longer, coarse, pigmented hair that may grow in response to sex hormones. The luteal phase is the second-half of the cycle and is more consistent in length, lasting 12 to 14 days in most individuals. Chest wall very thickened by oedema Uterine wall Oblique view of ribs Vertebra Pleural effusion Lungs Heart. Hypotension does not play a major role unless an unexpected large blood loss has occurred. Trichomonas is diagnosed in up to 35% of women presenting with vulvovaginitis complaints. Thyroglossal duct cysts are congenital but can enlarge if they become infected or during an upper respiratory infection. Breasts: assess developmental stage and evaluate for common findings include asymmetry or benign rubbery tumors called fibroadenomas. She gives a history of trauma to the area 1 month previously, after which she noted a "quarter size" lumpy area with no associated skin discoloration. Painful vesicular lesions appear at site of contact and can last for 1 to 3 weeks Directions: Each of the numbered items or incomplete statements in this section is followed by answers or by completions of the statement. Management Bacterial meningitis can progress rapidly and when this disease is suspected, antibiotic therapy should be instituted prior to diagnostic procedures. Studies in humans have demonstrated a risk to the fetus; therefore, the drug should not be administered during pregnancy. Bowel regimen medication is also provided with bisacodyl or glycerin suppository daily, and docusate plus senna. The obstetrical conjugate is the shortest anterior posterior diameter through which the fetal head must pass. Management Biopsy is generally avoided due to sampling error, risk of morbidity, and limited effect on therapy. Symptoms include severe dysmenorrhea, unilateral pelvic pain, chronic pelvic pain, and paravaginal mass. Operative gynecologic procedures hysteroscopy, dilation and curettage, tubal ligation, myomectomy, hysterectomy, and salpingo-oophorectomy. The presence of abnormal soft tissue in the middle ear with bone erosion is the hallmark of cholesteatoma. A brief history of the pregnancy and past obstetric history is taken, and temperature, blood pressure, pulse and urinalysis are recorded. She has been pushing for 2 hours and on examination the fetal head in determined to be occiput anterior with a cervical examination of complete dilatation, 100% effaced and 2 station. Controversy exists with regard to whether rosiglitazone causes increased coronary ischemic risk. The ductus arteriosus is no longer patent and becomes known as the ligamentum arteriosum.